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Quan s'indica una transfusió de sang
When are transfusions of fresh-frozen plasma given?
Despite its widespread use, plasma probably has the least-established indications out of all the blood components. Except in specific cases, it is preferable to plasma derivatives, in a concentrated and purified form which can be prescribed in precise doses, inactivated for potentially contaminating viruses. We currently have very efficacious and safe plasma derivatives for the majority of indications.

The risks associated with plasma transfusions include: circulatory overload, destruction of erythrocytes resulting from ABO incompatibility, anticoagulant toxicity, febrile and allergic reactions and a lung syndrome called TRALI which can be very serious.

•  What are the indications for plasma transfusions?

As in the case of a deficiency in coagulation factors or endogenous anticoagulants, fresh-frozen plasma transfusions are only indicated when the deficient concentrate does not exist or is not available. Indications as to when its use is established and has been demonstrated to be efficacious are as follows

The possibility of performing plasma transfusions is considered when there is both haemorrhagic syndrome and changes in coagulation test results. The following are some of the situations when these circumstances arise and when they need to be evaluated individually:

•  disseminated intravascular coagulation
•  in cases of overdose of oral anticoagulants (SintromR, AldocumarR etc.), with life-threatening haemorrhage as well as with patients who have to undergo extremely urgent bloody procedures
•  liver transplants
•  hepatopathy with diffuse haemorrhaging
•  massive transfusions
•  cirurgia extracorpòria
•  congenital coagulation deficiencies, in the absence of specific concentrate factors
Fresh-frozen plasma
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