Blood components
Fresh plasma from a single donor
DEFINITION
Plasma obtained by means of an aphaeresis procedure from a single donor.
HOW IT IS OBTAINED
By a cell separator, which obtains total blood from a donor, separates its elements with a centrifuge, collects the plasma and returns the other blood components to the donor.
COMPOSITION AND CHARACTERISTICS
Volume:
- Between 570 and 600 ml, when only one plasma unit is obtained. Approximately 220 ml, when, in addition to the plasma unit, other products are also obtained (red blood cells and/or platelets).
Contents in coagulation factors:
- Factor VIII 0.77 UI/ml (between 0.37 and 1.17)
- Factor V 0.94 UI/ml (between 0.56 and 1.32)
- Factor II 0.87 UI/ml (between 0.73 and 1.01)
- Fibrinogen 3.21 g/l (between 1.67 and 4.57)
ANALYSIS RESULTS
- ABO group and Rh factor.
- Irregular antibodies: negative.
- Surface antigen of the hepatitis B virus (HBs Ag): negative.
- Antibodies against the hepatitis C virus (Anti-HCV): negative.
- Antibodies against the Immunodeficiency virus (Anti-HIV 1+2): negative.
- Syphilis serology: negative.
- NAT of HCV (PCR): negative.
- NAT of HIV (PCR): negative.
- NAT of VHB (PCR): negative.
- Anti-Trypanosoma cruzi antibodies: negative (only carried out on donors with a risk of being carriers).
RECIPIENT
Collapsible plastic bags.
IDENTIFICATION
With labels containing the following data: name of the centre, type of product, ABO group and Rh (D) factor, unit number, date of extraction, expiry date, results of analysis, type of anticoagulant, preservation and administration conditions.
PRESERVATION
At -30ºC.
EXPIRY DATE
3 years.
HANDLING
Units of fresh plasma from a single donor can be divided into subunits.
OBSERVATIONS
Fresh plasma from a single donor is not used for transfusions. It is an intermediate product that it subject to quarantine or deactivated with methylene blue. If the original donor does not make another donation within the necessary time period, this plasma is sent to industries to manufacture derivatives.