R+D+I

The Banc de Sang i Teixits (Blood and Tissue Bank, BST) regards research as a strategic activity for providing services of the highest quality and safety, rapidly incorporating improvements in our field as they emerge, and working to devise new diagnostic and therapeutic tools.

Research

We conduct independent research projects and work on others in cooperation with every centre pertaining to the Catalan Health Institute, with the majority of centres in the Network of Public-Access Hospitals and with Catalan universities, and we also pursue strategic alliances with research centres around the world.

We have developed a new R&D Strategic Plan for 2017-2020. Download it in here (PDF).

At present, we are involved in 67 research and innovation projects at the BST. Within our organisation, 70 people dedicate part of their time to research.

The BST leads 4 RETOS projects in which it collaborates with IGTP, CMRB, Institut Josep Carreras, Hospital de la Fe and Center of Transfusions of the Valencian Community, with a total budget of almost 2,000,000€.

Funded projects

  • "Development and implementation of new molecular massive analysis tools for global approach to diagnosis and research of congenital coagulopathies" funded by Institute of Health Carlos III. File: PI15/01643
  • "Cardiopoiesis with biomatrixs to regenerate post-infarct scar: From bench to bedside (first-in-man trial)" funded by the Health Department of the Government of Catalonia through the call PERIS. File: SLT002/16/00234
  • "Hematopoietic regeneration from pluripotent stem cells" funded by the Health Department of the Government of Catalonia through the call PERIS. File: STL002/16/00299
  • "ADVANCECAT: Accelerator for the development of advanced therapies in Catalonia". Main objective: To promote technological development, innovation and quality research. This project is co-funded by the European Commission through the European Regional Development Fund (ERDF). File: COMRDI15-1-0013. This project aims to organize a Catalan network of centers involved in advanced therapies in order to innovate and advance as quickly as possible from the idea to the clinical application and / or the industrial production of this new type of therapies
  • "Euro-GTP II- Good Practices for demonstrating safety and quality through recipient follow-up". Aims to develop the good practices and methods needed for the correct evaluation of the clinical efficacy of the therapies with tissues and cells of human origin, thus allowing to demonstrate their quality and safety in patients receiving these products. BST has coordinated this project funded by the European Commission's 3rd Health Program (709567 -HP-PJ-2015) over the last 3 years, with the participation of 14 organizations from 11 European countries representing other tissue banks, competent authorities, research and application units of international level reference.
  • The Project FACTOCEL: Expansion of the facilities of a cellular medicines factory for regenerative medicine with file number PLE2009-0092 has been funded with the national program of internationalization of R&D, subprogram of promotion of international scientific cooperation (FCCI) PLAN -E, TYPE: STEM CEL INFRA
  • "Course: The role of eye banks in the corneal self-sufficiency program in Spain. Module 4". Activity funded by the Spanish Ministry Health Social Service & Equality
  • "Pericardial matrix with mesenchymal stem cells for the treatment of patients with infarcted myocardial tissue". This project is funded by the Ministry of Science Innovation and Universities and cofounded by the European Commission by the European Regional Development Fund  File: SAF2017-84324-C2-2-R
  • "TRANSPOSE: TRANSfusion and transplantation: PrOtection and SElection of donors" this project is funded by the European Commission. File: 738145
  • "ID-VITRORED: Obtaining in vitro red blood cells from IPSCS of donors with selected erythrocyte phenotypes and optimized by genomic editing, as an alternative to the current red cell panels ", file: RTC-2017-6367-1, funded by the State Agency of Universities - Ministry of Science, Innovation and Universities / FEDER Funds of the European Union with the main objective: To promote technological development, innovation and quality research.
  • "iPS-PANIA: Allogeneic IPSC from homozygous SCU units for high prevalence haplotypes ", file: RTC-2017-6000-1, funded by the State Agency of Universities - Ministry of Science, Innovation and Universities / FEDER Funds of the European Union with the objective Main: Promote technological development, innovation and quality research.
  •  "T-CELBANC: Creation of a national bank of specific T lymphocytes for immediate use in opportunistic post-transplant infections, "funded by the State Agency of Universities - Ministry of Science, Innovation and Universities / FEDER Funds of the European Union with the main objective: To promote the development technology, innovation and quality research.
  •  "JOINT ACTION: FacilitatinG the Authorisation of Preparation Processes for blood, tissues and cells (GAPP)" funded by the European Commission. File: 785269
  • "Approach to hereditary bleeding disorders of complex etiology by applying a common exome sequencing strategy" funded by the Institute of Health Carlos III. File: PI18/01492

Scientific output

By 2018 BST researchers published 31 articles in scientific journals that had an impact factor of 116. 45% of these publications are from the first quartile.

Patents

The BST has 4 patents granted in Spain, one granted in the United States, two granted by the European Patent Office and validated in several European countries and one granted in Mexico.